Title: verubecestat,a BACE1 inhibitor
Structure: C[C@]1(CS(=O)(=O)N(C(=N1)N)C)c2cc(ccc2F)NC(=O)c3ccc(cn3)F | Search PubChem
JOB ID: PGS1804126276


33 Targets were ranked by ShapeTanimoto. If necessary, please click arrow to sort table.
PDB#
TanimotoCombo
ShapeTanimoto
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Protein Name
UNIPROT_ID
UNIPROT_AC
1551.5550.8980.657Beta-secretase 1BACE1_HUMANP56817
641.0150.7980.26Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoformPK3CG_HUMANP48736
1251.070.7830.378Mitogen-activated protein kinase 14MK14_HUMANQ16539
290.9750.7630.383Serine/threonine-protein kinase GSK3BGSK3B_HUMANP49841
60.9070.7430.178Beta-2 adrenergic receptorADRB2_HUMANP07550
20.7980.7210.122cGMP-dependent 3',5'-cyclic phosphodiesterasePDE2A_HUMANO00408
40.8830.7090.226Cyclin-dependent kinase 5CDK5_HUMANQ00535
160.880.6820.243Epidermal growth factor receptorEGFR_HUMANP00533
140.830.6790.343cAMP-specific 3',5'-cyclic phosphodiesterase 4DPDE4D_HUMANQ08499
410.870.6770.279AcetylcholinesteraseACES_TORCAP04058
120.8430.6770.231Oxysterols receptor LXR-betaNR1H2_HUMANP55055
70.8630.6710.262cAMP-specific 3',5'-cyclic phosphodiesterase 4BPDE4B_HUMANQ07343
60.8110.6660.198High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9APDE9A_HUMANO76083
10.880.660.22Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoformPK3CB_MOUSEQ8BTI9
30.8560.6480.235cGMP-specific 3',5'-cyclic phosphodiesterasePDE5A_HUMANO76074
50.8640.6470.22Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1PIN1_HUMANQ13526
10.8110.6360.175Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoformPK3CD_MOUSEO35904
30.8080.6280.223Amine oxidase [flavin-containing] BAOFB_HUMANP27338
10.9040.6270.277Phosphatidylinositol 3-kinase catalytic subunit type 3PK3C3_HUMANQ8NEB9
20.8480.6270.221Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformPK3CA_HUMANP42336
20.7650.6090.156Caspase-6CASP6_HUMANP55212
70.7790.5830.242Oxysterols receptor LXR-alphaNR1H3_MOUSEQ9Z0Y9
10.790.5760.214CholinesteraseCHLE_HUMANP06276
190.7520.5670.2043-hydroxy-3-methylglutaryl-coenzyme A reductaseHMDH_HUMANP04035
40.7490.5570.206Caspase-3CASP3_HUMANP42574
10.7040.5540.15Arachidonate 12-lipoxygenase, 12S-typeLOX12_PIGP16469
20.6740.5410.133Acyl-coenzyme A:cholesterol acyltransferaseEST1_HUMANP23141
20.8650.5380.328Nitric oxide synthase, inducibleNOS2_HUMANP35228
10.7420.5280.215cAMP-specific 3',5'-cyclic phosphodiesterase 4APDE4A_HUMANP27815
10.5930.5260.067Arachidonate 15-lipoxygenaseLOX15_RABITP12530
10.6360.5040.132Endothelin-converting enzyme 1ECE1_HUMANP42892
10.6440.4590.185MyeloperoxidasePERM_HUMANP05164
10.7010.390.311Muscarinic acetylcholine receptor M2ACM2_HUMANP08172