ROCS-Based Target Fishing--Check result

Title: GSK3B inhibitor, J. Med. Chem., 2008, 51(7):2062
Structure: CC(=O)Nc1n[nH]c2ncc(cc12)c3ccccc3 | Search PubChem

JOB ID: PGS1808379813

33 Targets were ranked by ShapeTanimoto. If necessary, please click arrow to sort table.

PDB# ⇓ ⇑	TanimotoCombo ⇓ ⇑	ShapeTanimoto ⇓ ⇑	ColorTanimoto ⇓ ⇑	Protein Name ⇓ ⇑	UNIPROT_ID ⇓ ⇑	UNIPROT_AC ⇓ ⇑
29	1.126	0.846	0.361	Serine/threonine-protein kinase GSK3B	GSK3B_HUMAN	P49841
64	1.09	0.83	0.38	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	PK3CG_HUMAN	P48736
4	1.113	0.815	0.298	Cyclin-dependent kinase 5	CDK5_HUMAN	Q00535
1	0.939	0.771	0.168	Phosphatidylinositol 3-kinase catalytic subunit type 3	PK3C3_HUMAN	Q8NEB9
125	0.954	0.764	0.351	Mitogen-activated protein kinase 14	MK14_HUMAN	Q16539
41	1.001	0.757	0.276	Acetylcholinesterase	ACES_TORCA	P04058
7	0.943	0.755	0.188	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	PDE4B_HUMAN	Q07343
2	0.962	0.734	0.232	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	PK3CA_HUMAN	P42336
14	0.958	0.734	0.255	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	PDE4D_HUMAN	Q08499
2	0.915	0.731	0.184	Acyl-coenzyme A:cholesterol acyltransferase	EST1_HUMAN	P23141
155	0.93	0.714	0.284	Beta-secretase 1	BACE1_HUMAN	P56817
2	0.933	0.694	0.239	Caspase-6	CASP6_HUMAN	P55212
6	0.954	0.69	0.287	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	PDE9A_HUMAN	O76083
4	0.895	0.681	0.226	Caspase-3	CASP3_HUMAN	P42574
6	0.932	0.675	0.256	Beta-2 adrenergic receptor	ADRB2_HUMAN	P07550
16	0.949	0.673	0.335	Epidermal growth factor receptor	EGFR_HUMAN	P00533
1	0.891	0.652	0.238	Cholinesterase	CHLE_HUMAN	P06276
3	0.84	0.642	0.197	Amine oxidase [flavin-containing] B	AOFB_HUMAN	P27338
1	0.708	0.637	0.071	Arachidonate 15-lipoxygenase	LOX15_RABIT	P12530
1	0.792	0.617	0.175	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	PK3CD_MOUSE	O35904
1	0.819	0.605	0.214	cAMP-specific 3',5'-cyclic phosphodiesterase 4A	PDE4A_HUMAN	P27815
3	0.792	0.601	0.206	cGMP-specific 3',5'-cyclic phosphodiesterase	PDE5A_HUMAN	O76074
2	0.739	0.596	0.182	cGMP-dependent 3',5'-cyclic phosphodiesterase	PDE2A_HUMAN	O00408
5	0.819	0.592	0.281	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	PIN1_HUMAN	Q13526
1	0.765	0.579	0.186	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	PK3CB_MOUSE	Q8BTI9
2	0.821	0.571	0.25	Nitric oxide synthase, inducible	NOS2_HUMAN	P35228
12	0.767	0.571	0.214	Oxysterols receptor LXR-beta	NR1H2_HUMAN	P55055
7	0.762	0.524	0.238	Oxysterols receptor LXR-alpha	NR1H3_MOUSE	Q9Z0Y9
1	0.791	0.517	0.274	Myeloperoxidase	PERM_HUMAN	P05164
1	0.593	0.513	0.08	Endothelin-converting enzyme 1	ECE1_HUMAN	P42892
19	0.641	0.491	0.19	3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_HUMAN	P04035
1	0.576	0.488	0.088	Arachidonate 12-lipoxygenase, 12S-type	LOX12_PIG	P16469
1	0.764	0.444	0.32	Muscarinic acetylcholine receptor M2	ACM2_HUMAN	P08172

ROCS-Based Target Prediction