Title: MOA-B inhibitor,J. Med. Chem., 2014, 57 (15), pp 6679–6703 DOI: 10.1021/jm500729
Structure: O=C(Nc1ccc(Cl)c(Cl)c1)c3ccc2[nH]ncc2c3 | Search PubChem
JOB ID: PGS2700493855


33 Targets were ranked by ShapeTanimoto. If necessary, please click arrow to sort table.
PDB#
TanimotoCombo
ShapeTanimoto
ColorTanimoto
Protein Name
UNIPROT_ID
UNIPROT_AC
291.0380.8360.283Serine/threonine-protein kinase GSK3BGSK3B_HUMANP49841
641.150.8260.402Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoformPK3CG_HUMANP48736
31.0780.7940.299Amine oxidase [flavin-containing] BAOFB_HUMANP27338
60.9190.7820.215High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9APDE9A_HUMANO76083
1251.190.7760.491Mitogen-activated protein kinase 14MK14_HUMANQ16539
411.0110.7670.353AcetylcholinesteraseACES_MOUSEP21836
41.020.7550.287Cyclin-dependent kinase 5CDK5_HUMANQ00535
140.9530.7290.379cAMP-specific 3',5'-cyclic phosphodiesterase 4DPDE4D_HUMANQ08499
70.9370.7270.31cAMP-specific 3',5'-cyclic phosphodiesterase 4BPDE4B_HUMANQ07343
1551.0220.7210.331Beta-secretase 1BACE1_HUMANP56817
20.8970.7040.193Nitric oxide synthase, inducibleNOS2_HUMANP35228
20.9490.6950.253Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformPK3CA_HUMANP42336
10.9450.690.255Phosphatidylinositol 3-kinase catalytic subunit type 3PK3C3_HUMANQ8NEB9
10.8060.680.126CholinesteraseCHLE_HUMANP06276
40.8480.6610.3Caspase-3CASP3_HUMANP42574
10.740.6470.093Endothelin-converting enzyme 1ECE1_HUMANP42892
20.8130.6430.17Acyl-coenzyme A:cholesterol acyltransferaseEST1_HUMANP23141
20.7950.6390.156cGMP-dependent 3',5'-cyclic phosphodiesterasePDE2A_HUMANO00408
20.7630.6370.145Caspase-6CASP6_HUMANP55212
10.7940.630.163Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoformPK3CB_MOUSEQ8BTI9
50.7360.6220.236Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1PIN1_HUMANQ13526
120.8360.6050.368Oxysterols receptor LXR-betaNR1H2_HUMANP55055
60.810.6020.208Beta-2 adrenergic receptorADRB2_HUMANP07550
10.8320.6020.23cAMP-specific 3',5'-cyclic phosphodiesterase 4APDE4A_HUMANP27815
10.6740.5980.077Arachidonate 15-lipoxygenaseLOX15_RABITP12530
160.8570.5810.291Epidermal growth factor receptorEGFR_HUMANP00533
30.7250.570.234cGMP-specific 3',5'-cyclic phosphodiesterasePDE5A_HUMANO76074
70.7560.5650.261Oxysterols receptor LXR-alphaNR1H3_MOUSEQ9Z0Y9
10.8170.540.277Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoformPK3CD_MOUSEO35904
10.7950.5250.269Muscarinic acetylcholine receptor M2ACM2_HUMANP08172
10.7970.5080.29MyeloperoxidasePERM_HUMANP05164
10.7640.4980.266Arachidonate 12-lipoxygenase, 12S-typeLOX12_PIGP16469
190.7070.4820.233-hydroxy-3-methylglutaryl-coenzyme A reductaseHMDH_HUMANP04035