ROCS-Based Target Fishing--Check result

Title: Liu Jingxian Cancer
Structure: COc3ccc(c2oc1cc(OC)c(OC)c(O)c1c(=O)c2OC)cc3O | Search PubChem

JOB ID: PGS896247640

60 Targets were ranked by ShapeTanimoto. If necessary, please click arrow to sort table.

PDB# ⇓ ⇑	TanimotoCombo ⇓ ⇑	ShapeTanimoto ⇓ ⇑	ColorTanimoto ⇓ ⇑	Protein Name ⇓ ⇑	UNIPROT_ID ⇓ ⇑	UNIPROT_AC ⇓ ⇑
63	1.674	0.9358	0.7379	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	PK3CG_PIG	O02697
75	1.637	0.9297	0.7073	Peroxisome proliferator-activated receptor gamma	PPARG_HUMAN	P37231
20	1.207	0.9158	0.3745	Serine/threonine-protein kinase Chk2	CHK2_HUMAN	O96017
63	1.385	0.8998	0.485	Serine/threonine-protein kinase Chk1	CHK1_HUMAN	O14757
95	1.3	0.8952	0.508	Heat shock protein HSP 90-alpha	HS90A_HUMAN	P07900
21	1.392	0.8904	0.503	Estrogen receptor beta	ESR2_HUMAN	Q92731
180	1.492	0.89	0.6515	Cyclin-dependent kinase 2	CDK2_HUMAN	P24941
58	1.389	0.8844	0.5225	Estrogen receptor	ESR1_HUMAN	P03372
76	1.275	0.8743	0.4584	Carbonic anhydrase 2	CAH2_HUMAN	P00918
11	1.201	0.8533	0.417	Ephrin type-B receptor 4	EPHB4_HUMAN	P54760
2	1.327	0.852	0.4784	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	PK3CA_HUMAN	P42336
19	1.146	0.8472	0.3591	Stromelysin-1	MMP3_HUMAN	P08254
11	1.197	0.8438	0.3533	Insulin-like growth factor 1 receptor	IGF1R_HUMAN	P08069
14	1.154	0.8429	0.3872	Serine/threonine-protein kinase B-raf	BRAF_HUMAN	P15056
13	1.258	0.8359	0.4409	Progesterone receptor	PRGR_HUMAN	P06401
16	1.298	0.8323	0.4657	Epidermal growth factor receptor	EGFR_HUMAN	P00533
12	1.096	0.823	0.3722	Fibroblast growth factor receptor 1	FGFR1_HUMAN	P11362
21	1.232	0.8187	0.4288	Androgen receptor	ANDR_HUMAN	P10275
3	1.088	0.8169	0.2708	Retinoic acid receptor RXR-alpha	RXRA_HUMAN	P19793
24	1.196	0.8107	0.4279	Tyrosine-protein kinase ABL1	ABL1_MOUSE	P00520
50	1.234	0.8091	0.4286	Aurora kinase A	AURKA_HUMAN	O14965
31	1.142	0.808	0.4281	Kinesin-like protein KIF11	KIF11_HUMAN	P52732
7	1.426	0.7987	0.6271	Cyclin-dependent kinase 9	CDK9_HUMAN	P50750
28	1.118	0.7888	0.3514	Macrophage metalloelastase	MMP12_HUMAN	P39900
3	0.9973	0.785	0.2533	Dihydrofolate reductase	DRTS_PLAFK	P13922
1	1.113	0.7819	0.3315	Cytochrome P450 19A1	CP19A_HUMAN	P11511
7	1.193	0.7764	0.419	Proto-oncogene tyrosine-protein kinase Src	SRC_HUMAN	P12931
3	1.036	0.7706	0.2754	Induced myeloid leukemia cell differentiation protein Mcl-1	MCL1_HUMAN	Q07820
17	1.108	0.7583	0.4101	Leukotriene A-4 hydrolase	LKHA4_HUMAN	P09960
40	1.204	0.757	0.4474	Hepatocyte growth factor receptor	MET_HUMAN	P08581
31	0.9711	0.7569	0.3176	Vitamin D3 receptor	VDR_HUMAN	P11473
3	1.106	0.7546	0.3558	Histone deacetylase 4	HDAC4_HUMAN	P56524
13	1.081	0.7532	0.3826	RAC-alpha serine/threonine-protein kinase	AKT1_HUMAN	P31749
1	1.09	0.7524	0.3381	Serine/threonine-protein kinase receptor R3	ACVL1_HUMAN	P37023
9	1.075	0.7495	0.3356	Serine/threonine-protein kinase PLK1	PLK1_HUMAN	P53350
1	1.065	0.749	0.3159	Receptor tyrosine-protein kinase erbB-4	ERBB4_HUMAN	Q15303
2	1.146	0.7446	0.4013	HSP90AA1 protein	Q2VPJ6_HUMAN	Q2VPJ6
16	0.9709	0.7345	0.2743	E3 ubiquitin-protein ligase Mdm2	MDM2_HUMAN	Q00987
22	1.015	0.7312	0.3074	Collagenase 3	MMP13_HUMAN	P45452
2	1.02	0.7307	0.2892	Steroid 17-alpha-hydroxylase/17,20 lyase	CP17A_HUMAN	P05093
1	1.009	0.7306	0.2782	AKAP9-BRAF fusion protein	Q5IBP5_HUMAN	Q5IBP5
3	0.9802	0.7253	0.3375	Mast/stem cell growth factor receptor Kit	KIT_HUMAN	P10721
1	1.03	0.7229	0.3071	Cellular tumor antigen p53	P53_HUMAN	P04637
4	0.9225	0.722	0.3236	Thymidylate synthase	TYSY_HUMAN	P04818
6	1.016	0.7184	0.3553	Matrix metalloproteinase-9	MMP9_HUMAN	P14780
2	0.9685	0.7086	0.2599	Interstitial collagenase	MMP1_HUMAN	P03956
2	1.082	0.7077	0.3742	Programmed cell death 1 ligand 1	PD1L1_HUMAN	Q9NZQ7
4	0.9313	0.7054	0.3299	Bcl-2-like protein 1	B2CL1_HUMAN	Q07817
1	0.9327	0.6996	0.2331	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613
1	0.9872	0.6896	0.2976	Protein kinase C alpha type	KPCA_HUMAN	P17252
1	0.8819	0.6786	0.2033	Receptor tyrosine-protein kinase erbB-2	ERBB2_HUMAN	P04626
1	0.8669	0.6495	0.2174	High affinity nerve growth factor receptor	NTRK1_HUMAN	P04629
3	0.954	0.6362	0.3204	Nitric oxide synthase, endothelial	NOS3_HUMAN	P29474
1	0.9	0.6305	0.2695	Aurora kinase B	AURKB_HUMAN	Q96GD4
1	0.7928	0.576	0.2167	Ribosomal protein S6 kinase beta-1	KS6B1_HUMAN	P23443
1	0.8381	0.5721	0.266	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	PK3CB_MOUSE	Q8BTI9
1	0.796	0.5588	0.2371	Lethal(3)malignant brain tumor-like protein 1	LMBL1_HUMAN	Q9Y468
1	0.8068	0.5564	0.2504	C-X-C chemokine receptor type 4	CXCR4_HUMAN	P61073
1	0.8283	0.551	0.2773	Neprilysin	NEP_HUMAN	P08473
2	0.7548	0.5337	0.2505	Apoptosis regulator Bcl-2	BCL2_HUMAN	P10415

ROCS-Based Target Prediction